Cancer/Oncology , Rx required


Manufacturer- ALKEM LABS LTD.

Composition- DENOSUMAB-60MG


DENUB 60MG/1ML INJ belongs to a group of medicines called RANK ligand inhibitors used to treat osteoporosis in postmenopausal women and men who have an increased risk of fracture. DENUB 60MG/1ML INJ is also used to treat bone loss due to reduced testosterone level caused by surgery, due to the treatment with medicines such as glucocorticoids and in patients with prostate cancer. DENUB 60MG/1ML INJ may also be used to reduce the risk of fractures in people with multiple myeloma, giant cell tumour of the bone, and to treat high calcium levels caused due to cancer.

DENUB 60MG/1ML INJ contains ‘denosumab’, which works by blocking a receptor in the body which causes bone loss, thereby treats bone loss. DENUB 60MG/1ML INJ treats giant cell tumour of bone (GCTB) by blocking certain receptors in the tumour cells, thereby slows the tumour growth. DENUB 60MG/1ML INJ helps treat high calcium levels by decreasing bone breakdown as a breakdown of the bones releases calcium. DENUB 60MG/1ML INJ makes the bones stronger and less likely to break.

DENUB 60MG/1ML INJ will be administered by a healthcare professional; do not self-administer. You are advised to take DENUB 60MG/1ML INJ for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as bone/joint/muscle pain, arm/leg pain, abdominal discomfort, constipation, and painful/frequent urination. You are advised to talk to your doctor if you experience these side effects persistently.

DENUB 60MG/1ML INJ might cause osteonecrosis of the jaw; therefore, whilst on treatment with DENUB 60MG/1ML INJ, maintain good dental hygiene and receive regular dental check-ups. Avoid taking DENUB 60MG/1ML INJ if you are pregnant. Consult your doctor before taking DENUB 60MG/1ML INJ if you are breastfeeding. DENUB 60MG/1ML INJ is not recommended for children below 18years as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medicines to rule out any side effects.

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